Research Interests

1. Research on metabolism and cardiovascular and cerebrovascular diseases. Metabolism is closely related to the study of cardiovascular and cerebrovascular diseases. The development and prognosis of cardiovascular and cerebrovascular diseases (including myocardial infarction and stroke) have metabolic participation. Metabolic regulation is an important research field after genetic and protein regulation. Our team has also discovered some of the new pathophysiological mechanisms and clinical related research on metabolic molecules and related proteins on cardiovascular and cerebrovascular diseases, including the impact of signaling pathways such as amber acid metabolism, lipid metabolism, and lipoprotein on cardiovascular and cerebrovascular systems.


2. Intestinal flora metabolism. The intestinal flora is a complex system. It has a balanced and non -steady -state balance. These balanced breaks can bring different metabolites. Due to the existence of these metabolites, it affects other outside the intestine. Organs, such as cardiovascular and cerebrovascular systems, have produced new theoretical systems such as intestinal axis, intestinal and brain shafts, and intestinal liver axis. Our team discovered a series of new intestinal flora metabolites such as TMAVA (trimethyl-5-aminovaleric acid) on the pathological and physiological effects of the heart and the liver, and also found that TMAO (trimethylamine oxide) that has been well known is well known. New pathological functions such as new mechanisms in stroke and pulmonary hypertension.


3. Metabolic research on other diseases. In addition to having a huge effect on cardiovascular and cerebrovascular diseases, metabolic diseases can also affect diseases other than cardiovascular and cerebrovascular diseases such as diabetes. The mechanism of contemporary can not only affect metabolic diseases such as diabetes and kidney disease, fatty liver, but also affects the vascular and tumors in the tumor through metabolic pathways. Through metabolic intervention and metabolic related regulation, we can provide new ideas and insights on the treatment of diseases.


4. Combining new materials and new technologies to carry out transformation of cardiovascular and cerebrovascular related transformation. The application of cardiovascular and cerebrovascular function, including the application and research of treatment and in vitro diagnostic technology. Combining nano-technology and probe materials to carry out the diagnosis and treatment of cardiovascular and cerebrovascular, marking specific cells such as inflammatory cells, and conducting drug transportation of specific cells, so that the diagnosis and treatment of cardiovascular and cerebrovascular can continue to develop on the new track. Carry out diagnostic studies including biomass spectrometry technology, and apply new monitoring and diagnostic technology to the prevention and prognosis of cardiovascular and cerebrovascular diseases.