Lipids have a variety of important biological functions, and abnormal lipid metabolism is an important factor in the occurrence and development of atherosclerosis. The Lipid Metabolism and Atherosclerosis Center aims to combine a variety of technologies such as biological mass spectrometry to address physiological and pathological (atherosclerosis, stroke, metabolic syndrome) states, and to treat various lipids including phospholipids, sphingolipids, and glycerides. It is also used to analyze the lipid molecules related to the metabolism of intestinal flora, study lipid differences in complex samples such as plasma, tissues or other biological fluids, and clarify lipid metabolism and lipid functions in different disease states, and combining genetically engineered animal models to study the biological functions of differential lipids in molecular mechanisms.

On the clinical side, establish a large sample database of atherosclerotic cerebrovascular disease, conduct its epidemiological, genetic and epigenetic research, and focus on mining the data on blood lipid metabolism testing items and lipid-lowering drugs in the library Information, while screening new lipid markers through clinical samples of different diseases to achieve early diagnosis and treatment of diseases. Constructing a lipidomics platform, integrating clinicians and researchers in the lipid field, using cutting-edge biological technologies including mass spectrometry, flow cytometry, and bioimaging technology, combined with basic vascular function research, to complete new clinical diagnosis and disease classification/Mechanism and drug target development, and jointly promote the development of diagnosis and treatment of cardiovascular and cerebrovascular (including cerebrovascular and peripheral blood vessels).

Overall view of laboratory